Recombinant 2019-nCoV S protein RBD(C-mFc)

Item number: EPT092
Availability: In Stock
$399.00
$399.00
Please hurry! Only 100 left in stock

Documents

Size: 50ug
Subtotal: $399.00
10 customers are viewing this product

Customized & fast shipping

Terms and Conditions

Recombinant 2019-nCoV S protein RBD(C-mFc)

Recombinant 2019-nCoV S protein RBD(C-mFc)

$399.00

Recombinant 2019-nCoV S protein RBD(C-mFc)

$399.00
Size: 50ug
Description
Recombinant SARS-CoV-2 S protein RBD Protein is produced by our Mammalian expression system and the target gene encoding Asn331-Val524 is expressed with a mFc tag at the C-terminus.
Accession
QHD43416.1
Molecular weight
47.9kDa
Apparent molecular weight
50-60kDa, reducing conditions
Other names
S protein RBD; 2019-nCoV S protein RBD
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Biological activity
Immobilized Human ACE-2-His(Cat#C419)at 10μg/ml (100μl/well) can bind 2019-nCoV S Protein RBD-mFc(Cat#DRA32). The ED50 of 2019-nCoV S Protein RBD-mFc(Cat#DRA32) is 19.90 ng/ml.
Storage
Reconstituted protein solution should be stored at ≤ -20°C.
Delivery condition
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Related Products

Recently Viewed Products