Recombinant Human Sting (N-Sumo-6His)

Item number: EPT179
Availability: In Stock
$589.00
$589.00
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Size: 50ug
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Recombinant Human Sting (N-Sumo-6His)

Recombinant Human Sting (N-Sumo-6His)

$589.00

Recombinant Human Sting (N-Sumo-6His)

$589.00
Size: 50ug
Description
Recombinant Human Stimulator of Interferon Genes Protein is produced by our E.coli expression system and the target gene encoding Val155-Val341 is expressed with a 6His, Sumo tag at the N-terminus.
Accession
Q86WV6
Molecular weight
33.8 KDa
Apparent molecular weight
35 KDa, reducing conditions
Other names
Stimulator of interferon genes protein;TMEM173;Mediator of IRF3 activation;sting;
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Storage
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Delivery condition
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.

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