Recombinant Mouse Thrombomodulin (C-6His)

Item number: EPT230
Availability: In Stock
$279.00
$279.00
Please hurry! Only 100 left in stock

Documents

Size: 10ug
Subtotal: $279.00
×

Request a Quote

Thank you! We’ll contact you soon.

10 customers are viewing this product

Customized & fast shipping

Terms and Conditions

Recombinant Mouse Thrombomodulin (C-6His)

Recombinant Mouse Thrombomodulin (C-6His)

$279.00

Recombinant Mouse Thrombomodulin (C-6His)

$279.00
Size: 10ug
Description
Recombinant Mouse Thrombomodulin is produced by our Mammalian expression system and the target gene encoding Leu17-Ser517 is expressed with a 6His tag at the C-terminus.
Accession
P15306
Molecular weight
54.6 KDa
Apparent molecular weight
85-90 KDa, reducing conditions
Other names
Thrombomodulin; TM; Fetomodulin; CD141; BDCA-3; Thbd
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Storage
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Delivery condition
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin, EGF-like, transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells, THBD inhibits coagulation and fibrinolysis. It functions as a cell surface receptor and an essential cofactor for active thrombin, which in turn activates protein C and thrombinactivatable fibrinolysis inhibitor (TAFI), also known as carboxypeptidase B2 (CPB2). In addition, THBD gene polymorphisims are associated with human disease and THBD plays a role in thrombosis, stroke, arteriosclerosis, and cancer.

Related Products

Recently Viewed Products