Product Overview
Product Overview
Applications
IHC;IF;WB
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Endosome . Endosome membrane. Nucleus . In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER (PubMed:20674546, PubMed:17909029). Endocytosed upon activation by ligand (PubMed:2790960, PubMed:17182860, PubMed:27153536, PubMed:17909029). Colocalized with GPER1 in the nucleus of estrogen agonist-induced cancer-associated fibroblasts (CAF) (PubMed:20551055). .; [Isoform 2]: Secreted.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1956
Human swiss prot no
P00533
Immunogen
Synthesized peptide derived from human EGFR (Phospho-Tyr998)
Isotype
IgG
Observed band
175kD
Product weight
0.005kg
Reactivity
Human; Mouse; Rat
Recommended dilutions
IHC-p 1:50-200, WB 1:500-2000
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Background
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],
Product Citations
Product Citations
More Info
More Info
EGFR (Phospho-Tyr998) rabbit pAb
EGFR (Phospho-Tyr998) rabbit pAb
Vendor: ELK Biotechnology
SKU: ES16782
Regular price
$148.00 USD
Sale price
$148.00 USD
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC;IF;WB
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Endosome . Endosome membrane. Nucleus . In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER (PubMed:20674546, PubMed:17909029). Endocytosed upon activation by ligand (PubMed:2790960, PubMed:17182860, PubMed:27153536, PubMed:17909029). Colocalized with GPER1 in the nucleus of estrogen agonist-induced cancer-associated fibroblasts (CAF) (PubMed:20551055). .; [Isoform 2]: Secreted.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1956
Human swiss prot no
P00533
Immunogen
Synthesized peptide derived from human EGFR (Phospho-Tyr998)
Isotype
IgG
Observed band
175kD
Product weight
0.005kg
Reactivity
Human; Mouse; Rat
Recommended dilutions
IHC-p 1:50-200, WB 1:500-2000
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Background
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],
Product Citations
Product Citations
More Info
More Info
EGFR (Phospho-Tyr998) rabbit pAb
Regular price
$148.00 USD
Sale price
$148.00 USD
Regular price
Unit price
/per
