Product Overview
Product Overview
Applications
WB;IF;ELISA
Cellular localization
Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm, cytosol. Cytoplasmic vesicle. After ligand binding, both receptor and ligand are rapidly internalized. Can translocate to the nucleus after internalization, or by translocation from the endoplasmic reticulum or Golgi apparatus to the cytosol, and from there to the nucleus.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2260
Human swiss prot no
P11362
Immunogen
The antiserum was produced against synthesized peptide derived from human FGFR1 around the phosphorylation site of Tyr154. AA range:121-170
Isotype
IgG
Observed band
145 91kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Background
Background
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome,
Product Citations
Product Citations
More Info
More Info
Flg (phospho Tyr154) rabbit pAb
Flg (phospho Tyr154) rabbit pAb
Vendor: ELK Biotechnology
SKU: ES1445
Regular price
$148.00 USD
Sale price
$148.00 USD
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IF;ELISA
Cellular localization
Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm, cytosol. Cytoplasmic vesicle. After ligand binding, both receptor and ligand are rapidly internalized. Can translocate to the nucleus after internalization, or by translocation from the endoplasmic reticulum or Golgi apparatus to the cytosol, and from there to the nucleus.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2260
Human swiss prot no
P11362
Immunogen
The antiserum was produced against synthesized peptide derived from human FGFR1 around the phosphorylation site of Tyr154. AA range:121-170
Isotype
IgG
Observed band
145 91kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Background
Background
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome,
Product Citations
Product Citations
More Info
More Info
Flg (phospho Tyr154) rabbit pAb
Regular price
$148.00 USD
Sale price
$148.00 USD
Regular price
Unit price
/per
