Product Overview
Product Overview
Applications
IHC
Cellular localization
Cell membrane, Cytoplasm, Membrane
Clonality
Monoclonal
Concentration
1mg/mL
Geneid human
197259
Human swiss prot no
Q8NB16
Immunogen
Synthetic Peptide
Isotype
IgG1
Observed band
54kDa
Product weight
0.005kg
Reactivity
Human
Recommended dilutions
IHC 1:100-200
Source
Mouse
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Documents
Documents
Documents
Background
Background
Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.
Product Citations
Product Citations
More Info
More Info
MLKL (8H7) Mouse mAb
MLKL (8H7) Mouse mAb
Vendor: ELK Biotechnology
SKU: EM1328
Regular price
$148.00 USD
Sale price
$148.00 USD
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC
Cellular localization
Cell membrane, Cytoplasm, Membrane
Clonality
Monoclonal
Concentration
1mg/mL
Geneid human
197259
Human swiss prot no
Q8NB16
Immunogen
Synthetic Peptide
Isotype
IgG1
Observed band
54kDa
Product weight
0.005kg
Reactivity
Human
Recommended dilutions
IHC 1:100-200
Source
Mouse
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Documents
Documents
Documents
Background
Background
Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.
Product Citations
Product Citations
More Info
More Info
MLKL (8H7) Mouse mAb
Regular price
$148.00 USD
Sale price
$148.00 USD
Regular price
Unit price
/per
