ABHD12 rabbit pAb

ABHD12 rabbit pAb

Item number: ES1571
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ABHD12 rabbit pAb

ABHD12 rabbit pAb

$148.00

ABHD12 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human ABHD12. AA range:231-280
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
45kD
Geneid human
26090
Human swiss prot no
Q8N2K0
Cellular localization
Endoplasmic reticulum membrane ; Single-pass membrane protein .
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011],

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