ACCα rabbit pAb

ACCα rabbit pAb

Item number: ES5739
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ACCα rabbit pAb

ACCα rabbit pAb

$148.00

ACCα rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat;Bovine;Canine
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human Acetyl-CoA Carboxylase. AA range:46-95
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
265kD
Geneid human
31
Human swiss prot no
Q13085
Cellular localization
Cytoplasm, cytosol .
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

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