ACHB3 rabbit pAb

Item number: ES9918
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ACHB3 rabbit pAb

$148.00

ACHB3 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 160-240
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
50kD
Geneid human
1142
Human swiss prot no
Q05901
Cellular localization
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]). Elliott et al. (1996) [PubMed 8906617] stated that the proposed structure for each subunit is a conserved N

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