Apaf-1-ALT rabbit pAb

Apaf-1-ALT rabbit pAb

Item number: ES1672
Availability: In Stock
$148.00
$148.00
Please hurry! Only 100 left in stock

Documents

Size: 50μL
Subtotal: $148.00
10 customers are viewing this product

Customized & fast shipping

Terms and Conditions

Apaf-1-ALT rabbit pAb

Apaf-1-ALT rabbit pAb

$148.00

Apaf-1-ALT rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human APAF-1-ALT. AA range:289-338
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
27kD
Geneid human
317
Human swiss prot no
O14727-6
Cellular localization
Cytoplasm .
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Related Products

Recently Viewed Products