API5 rabbit pAb

API5 rabbit pAb

Item number: ES1678
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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API5 rabbit pAb

API5 rabbit pAb

$148.00

API5 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human API-5. AA range:421-470
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
58kD
Geneid human
8539
Human swiss prot no
Q9BZZ5
Cellular localization
Nucleus . Cytoplasm . Mainly nuclear. Can also be cytoplasmic.; [Isoform 3]: Cytoplasm.
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],

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