APPL1 rabbit pAb

APPL1 rabbit pAb

Item number: ES1684
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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APPL1 rabbit pAb

APPL1 rabbit pAb

$148.00

APPL1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human APPL1. AA range:121-170
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
80kD
Geneid human
26060
Human swiss prot no
Q9UKG1
Cellular localization
Early endosome membrane ; Peripheral membrane protein . Nucleus . Cytoplasm . Endosome . Cell projection, ruffle . Cytoplasmic vesicle, phagosome . Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF. .
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1(APPL1) Homo sapiens The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008],

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