APS rabbit pAb

APS rabbit pAb

Item number: ES4517
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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APS rabbit pAb

APS rabbit pAb

$148.00

APS rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from the Internal region of human APS.
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
67kD
Geneid human
10603
Human swiss prot no
O14492
Cellular localization
Cytoplasm . Cell membrane . Cytoplasmic before PDGF stimulation. After PDGF stimulation, localized at the cell membrane and peripheral region.
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009],

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