APTX rabbit pAb

APTX rabbit pAb

Item number: ES11441
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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APTX rabbit pAb

APTX rabbit pAb

$148.00

APTX rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 11-60
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
39kD
Geneid human
54840
Human swiss prot no
Q7Z2E3
Cellular localization
Nucleus, nucleoplasm . Nucleus, nucleolus . Upon genotoxic stress, colocalizes with XRCC1 at sites of DNA damage (PubMed:15380105). Colocalizes with MDC1 at sites of DNA double-strand breaks (PubMed:20008512). Interaction with NCL is required for nucleolar localization (PubMed:16777843). .; [Isoform 12]: Cytoplasm .
aprataxin(APTX) Homo sapiens This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010],

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