AR-β2 rabbit pAb
AR-β2 rabbit pAb

AR-β2 rabbit pAb

Item number: ES3778
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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AR-β2 rabbit pAb

AR-β2 rabbit pAb

$148.00

AR-β2 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from AR-β2 . at AA range: 300-380
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
46kD
Geneid human
154
Human swiss prot no
P07550
Cellular localization
Cell membrane ; Multi-pass membrane protein . Early endosome . Golgi apparatus . Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325). Activated receptors are also detected within the Golgi apparatus (PubMed:27481942). .
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008],

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