ARI1A rabbit pAb

ARI1A rabbit pAb

Item number: ES9020
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ARI1A rabbit pAb

ARI1A rabbit pAb

$148.00

ARI1A rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
IHC;IF
Source
Rabbit
Recommended dilutions
IHC-p 1:50-300
Immunogen
Synthesized peptide derived from human protein . at AA range: 1270-1350
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
251kD
Geneid human
8289
Human swiss prot no
O14497
Cellular localization
Nucleus .
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through eit

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