Arkadia rabbit pAb

Arkadia rabbit pAb

Item number: ES6675
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Arkadia rabbit pAb

Arkadia rabbit pAb

$148.00

Arkadia rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human RNF111. AA range:901-950
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
110kD
Geneid human
54778
Human swiss prot no
Q6ZNA4
Cellular localization
Nucleus . Cytoplasm . Nucleus, PML body . Upon TGF-beta treatment, translocates from nucleus to cytosol. .
ring finger protein 111(RNF111) Homo sapiens The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012],

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