ARVC rabbit pAb

ARVC rabbit pAb

Item number: ES18243
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ARVC rabbit pAb

ARVC rabbit pAb

$148.00

ARVC rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human; Mouse
Applications
WB
Source
Rabbit
Recommended dilutions
WB 1:500-2000
Immunogen
Synthesized peptide derived from human ARVC AA range: 563-613
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
105kD
Geneid human
421
Human swiss prot no
O00192
Cellular localization
Cell junction .
Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. [provided by RefSeq, Jun 2010],

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