Arylsulfatase G rabbit pAb

Arylsulfatase G rabbit pAb

Item number: ES5270
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Arylsulfatase G rabbit pAb

Arylsulfatase G rabbit pAb

$148.00

Arylsulfatase G rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human ARSG. AA range:251-300
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
65kD
Geneid human
22901
Human swiss prot no
Q96EG1
Cellular localization
Lysosome . The 63-kDa precursor protein localizes to pre-lysosomal compartments and tightly associates with organelle membranes, most likely the endoplasmic reticulum. In contrast, proteolytically processed fragments of 34-, 18- and 10-kDa are found in lysosomal fractions and lose their membrane association. .
The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012],

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