ASCC1 rabbit pAb

ASCC1 rabbit pAb

Item number: ES18235
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ASCC1 rabbit pAb

ASCC1 rabbit pAb

$148.00

ASCC1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human; Mouse
Applications
WB
Source
Rabbit
Recommended dilutions
WB 1:500-2000
Immunogen
Synthesized peptide derived from human ASCC1 AA range: 289-339
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
51008
Human swiss prot no
Q8N9N2
Cellular localization
Nucleus . Nucleus speckle . Colocalizes with PRPF8 in nuclear speckles in the absence of DNA damage. .
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

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