ASPM rabbit pAb

ASPM rabbit pAb

Item number: ES10611
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ASPM rabbit pAb

ASPM rabbit pAb

$148.00

ASPM rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
IHC;IF
Source
Rabbit
Recommended dilutions
IHC-p 1:50-300
Immunogen
Synthesized peptide derived from human protein . at AA range: 1230-1310
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
382kD
Geneid human
259266
Human swiss prot no
Q8IZT6
Cellular localization
Cytoplasm . Cytoplasm, cytoskeleton, spindle . Nucleus . The nuclear-cytoplasmic distribution could be regulated by the availability of calmodulin (By similarity). Localizes to spindle poles during mitosis (PubMed:19690332). Associates with microtubule minus ends (By similarity). .
This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011],

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