ATF-1 (phospho Ser63) rabbit pAb

ATF-1 (phospho Ser63) rabbit pAb

Item number: ES6326
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ATF-1 (phospho Ser63) rabbit pAb

ATF-1 (phospho Ser63) rabbit pAb

$148.00

ATF-1 (phospho Ser63) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human ATF1 around the phosphorylation site of Ser63. AA range:31-80
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
29kD
Geneid human
466
Human swiss prot no
P18846
Cellular localization
Nucleus .
activating transcription factor 1(ATF1) Homo sapiens This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chro

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