ATG13 Rabbit pAb
ATG13 Rabbit pAb

ATG13 Rabbit pAb

Item number: ES20862
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ATG13 Rabbit pAb

ATG13 Rabbit pAb

$148.00

ATG13 Rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human; Mouse;Rat
Applications
IHC;WB
Source
Rabbit
Recommended dilutions
IHC-p1:50-200 ,WB 1:1000-2000
Immunogen
Synthesized peptide derived from human ATG13 AA range: 182-232
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
72kD
Geneid human
9776
Human swiss prot no
O75143
Cellular localization
Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .
Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.

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