Atg4D rabbit pAb

Atg4D rabbit pAb

Item number: ES7792
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Atg4D rabbit pAb

Atg4D rabbit pAb

$148.00

Atg4D rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from the Internal region of human Atg4D.
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
45kD
Geneid human
84971
Human swiss prot no
Q86TL0
Cellular localization
[Cysteine protease ATG4D]: Cytoplasm .; [Cysteine protease ATG4D, mitochondrial]: Cytoplasm . Mitochondrion matrix . Imported into mitochondrial matrix after cleavage by CASP3 during oxidative stress and cell death. .
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

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