ATG5 Rabbit rabbit pAb

ATG5 Rabbit rabbit pAb

Item number: ES20826
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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ATG5 Rabbit rabbit pAb

ATG5 Rabbit rabbit pAb

$148.00

ATG5 Rabbit rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF
Source
Rabbit
Recommended dilutions
IHC-p 1:50-300,WB 1:500-2000
Immunogen
Recombinant Protein of ATG5
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
32kD
Geneid human
9494
Human swiss prot no
Q9H1Y0
Cellular localization
Cytoplasm . Preautophagosomal structure membrane; Peripheral membrane protein. Colocalizes with nonmuscle actin. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme. .
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015],

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