AVP Receptor V2 rabbit pAb
AVP Receptor V2 rabbit pAb

AVP Receptor V2 rabbit pAb

Item number: ES8846
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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AVP Receptor V2 rabbit pAb

AVP Receptor V2 rabbit pAb

$148.00

AVP Receptor V2 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000, ELISA 1:10000-20000
Immunogen
Synthesized peptide derived from human AVP Receptor V2. at AA range: 1-50
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
57kD
Geneid human
554
Human swiss prot no
P30518
Cellular localization
Cell membrane ; Multi-pass membrane protein .
This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus

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