Bad (phospho Ser112) rabbit pAb

Bad (phospho Ser112) rabbit pAb

Item number: ES1269
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Bad (phospho Ser112) rabbit pAb

Bad (phospho Ser112) rabbit pAb

$148.00

Bad (phospho Ser112) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human BAD around the phosphorylation site of Ser112. AA range:78-127
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
572
Human swiss prot no
Q92934
Cellular localization
Mitochondrion outer membrane. Cytoplasm . Colocalizes with HIF3A in the cytoplasm (By similarity). Upon phosphorylation, locates to the cytoplasm. .
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008],

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