Bamacan (Phospho-Ser1083) rabbit pAb

Bamacan (Phospho-Ser1083) rabbit pAb

Item number: ES18099
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Bamacan (Phospho-Ser1083) rabbit pAb

Bamacan (Phospho-Ser1083) rabbit pAb

$148.00

Bamacan (Phospho-Ser1083) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human; Mouse; Rat
Applications
IHC;IF;WB
Source
Rabbit
Recommended dilutions
IHC-p 1:50-200, WB 1:500-2000
Immunogen
Synthesized peptide derived from human Bamacan (Phospho-Ser1083)
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
145kD
Geneid human
9126
Human swiss prot no
Q9UQE7
Cellular localization
Nucleus . Chromosome . Chromosome, centromere . Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation. The phosphorylated form at Ser-1083 is preferentially associated with unsynapsed chromosomal regions (By similarity). .
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008],

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