Bcl-2 Mouse mAb

Bcl-2 Mouse mAb

Item number: EM1041
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Bcl-2 Mouse mAb

Bcl-2 Mouse mAb

$148.00

Bcl-2 Mouse mAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human, Rat, Mouse
Applications
WB, IHC, IF
Source
Mouse
Recommended dilutions
WB 1:1,000-2,000 IHC 1:200 IF 1:100-200
Immunogen
Synthetic Peptide
Isotype
IgG1
Clonality
Monoclonal
Concentration
1mg/mL
Observed band
26kDa
Geneid human
596
Human swiss prot no
P10415
Cellular localization
Mitochondrion outer membrane,Nucleus membrane,Endoplasmic reticulum membrane
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.

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