Beclin-1 rabbit pAb

Item number: ES8481
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Beclin-1 rabbit pAb

$148.00

Beclin-1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Chicken
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000, ELISA 1:10000-20000
Immunogen
Synthesized peptide derived from Beclin-1 . at AA range: 110-190
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
55kD
Geneid human
8678
Human swiss prot no
Q14457
Cellular localization
Cytoplasm . Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Endosome . Cytoplasmic vesicle, autophagosome . Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). .; [Beclin-1-C 35 kDa]: Mitochondrion . Nucleus . Cytoplasm .; [Beclin-1-C 37 kDa]: Mitochondrion .
beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

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