BinCARD rabbit pAb

BinCARD rabbit pAb

Item number: ES7746
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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BinCARD rabbit pAb

BinCARD rabbit pAb

$148.00

BinCARD rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human C9orf89. AA range:21-70
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
84270
Human swiss prot no
Q96LW7
Cellular localization
[Isoform 1]: Nucleus . Coexpression with BCL10 induced translocation from nucleus to cytosol.; [Isoform 2]: Endoplasmic reticulum membrane ; Single-pass membrane protein . Mitochondrion membrane ; Single-pass membrane protein .
function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.,PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CARD domain.,subcellular location:Co-expression with BCL10 induced translocation from nucleus to cytosol.,subunit:Associates with BCL10 by CARD-CARD interaction.,tissue specificity:Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.,

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