BLNK rabbit pAb

BLNK rabbit pAb

Item number: ES1773
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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BLNK rabbit pAb

BLNK rabbit pAb

$148.00

BLNK rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human BLNK. AA range:62-111
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
50kD
Geneid human
29760
Human swiss prot no
Q8WV28
Cellular localization
Cytoplasm . Cell membrane . BCR activation results in the translocation to membrane fraction.
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012],

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