Bmi-1 Rabbit pAb(F270)

Item number: ES20814
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Bmi-1 Rabbit pAb(F270)

$148.00

Bmi-1 Rabbit pAb(F270)

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human
Applications
WB
Source
Rabbit
Recommended dilutions
WB 1:500-2000
Immunogen
Recombinant Protein derived from human Bmi-1
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
37-43kD
Geneid human
100532731
Human swiss prot no
P35226
Cellular localization
Nucleus . Cytoplasm .
BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],

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