BMPR-IB rabbit pAb

BMPR-IB rabbit pAb

Item number: ES8793
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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BMPR-IB rabbit pAb

BMPR-IB rabbit pAb

$148.00

BMPR-IB rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen
Synthetic peptide from human protein at AA range: 21-70
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
658
Human swiss prot no
O00238
Cellular localization
Cell membrane ; Single-pass type I membrane protein .
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for thi

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