Bombesin Receptor 2 Rabbit pAb

Bombesin Receptor 2 Rabbit pAb

Item number: ES20813
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Bombesin Receptor 2 Rabbit pAb

Bombesin Receptor 2 Rabbit pAb

$148.00

Bombesin Receptor 2 Rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Rat;Mouse
Applications
WB;IHC;IF
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
Synthetic Peptide of Bombesin Receptor 2
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
50-70kD
Geneid human
2925
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

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