BRE rabbit pAb

Item number: ES8066
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Vareum

BRE rabbit pAb

$148.00

BRE rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human BRE. AA range:325-374
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
47kD
Geneid human
9577
Human swiss prot no
Q9NXR7
Cellular localization
Cytoplasm . Nucleus . Localizes at sites of DNA damage at double-strand breaks (DSBs). .
This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016],

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