Brg-1 rabbit pAb

Brg-1 rabbit pAb

Item number: ES7238
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Brg-1 rabbit pAb

Brg-1 rabbit pAb

$148.00

Brg-1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB; IF;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000; IF/ICC 1:100-500;ELISA 1:5000-20000
Immunogen
The antiserum was produced against synthesized peptide derived from human Brg-1. AA range:1565-1614
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
200kD
Geneid human
6597
Human swiss prot no
P51532
Cellular localization
Nucleus . Colocalizes with long non-coding RNA Evf2 in nuclear RNA clouds. .
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],

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