BubR1 rabbit pAb

BubR1 rabbit pAb

Item number: ES1801
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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BubR1 rabbit pAb

BubR1 rabbit pAb

$148.00

BubR1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human BUB1B. AA range:341-390
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
130kD
Geneid human
701
Human swiss prot no
O60566
Cellular localization
Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic in interphase cells. Associates with the kinetochores in early prophase. Kinetochore localization requires BUB1, PLK1 and KNL1.
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008],

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