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BYST rabbit pAb

BYST rabbit pAb

Item number: ES17938
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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BYST rabbit pAb

BYST rabbit pAb

$148.00

BYST rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human; Mouse;Rat
Applications
WB
Source
Rabbit
Recommended dilutions
WB 1:500-2000
Immunogen
Synthesized peptide derived from human BYST AA range: 127-177
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
705
Human swiss prot no
Q13895
Cellular localization
Cytoplasm . Nucleus, nucleolus . Associated with 40S ribosomal subunits.
Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi. [provided by RefSeq, Jul 2008],

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