C/EBP β (Acetyl Lys265) rabbit pAb

Vendor: ELK Biotechnology

SKU: ES20059

$148.00

Shipping calculated at checkout.

Documents

Manual

Available in stock (100)

Size: 50μL

50μL 100μL

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Product Overview

Applications

WB; ELISA

Cellular localization

Nucleus . Cytoplasm . Translocates to the nucleus when phosphorylated at Ser-288. In T-cells when sumoylated drawn to pericentric heterochromatin thereby allowing proliferation (By similarity). .

Clonality

Polyclonal

Concentration

1 mg/ml

Cost per item

74

Geneid human

1051

Human swiss prot no

P17676

Immunogen

Synthesized peptide derived from human C/EBP β (Acetyl Lys265)

Isotype

IgG

Observed band

40kD

Product weight

0.005kg

Reactivity

Human;Mouse;Rat

Recommended dilutions

WB 1:1000-2000 ELISA 1:5000-20000

Source

Rabbit

Storage

-20°C/1 year

Documents

Manual

Background

function:Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'.,PTM:Sumoylated by polymeric chains of SUMO2 or SUMO3.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha, delta and gamma. Interacts with TRIM28 and PTGES2.,tissue specificity:Expressed at low levels in the lung, kidney and spleen.,

C/EBP β (Acetyl Lys265) rabbit pAb