C/EBP β (Acetyl Lys265) rabbit pAb

Item number: ES20059
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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C/EBP β (Acetyl Lys265) rabbit pAb

$148.00

C/EBP β (Acetyl Lys265) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB; ELISA
Source
Rabbit
Recommended dilutions
WB 1:1000-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human C/EBP β (Acetyl Lys265)
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
40kD
Geneid human
1051
Human swiss prot no
P17676
Cellular localization
Nucleus . Cytoplasm . Translocates to the nucleus when phosphorylated at Ser-288. In T-cells when sumoylated drawn to pericentric heterochromatin thereby allowing proliferation (By similarity). .
function:Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'.,PTM:Sumoylated by polymeric chains of SUMO2 or SUMO3.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha, delta and gamma. Interacts with TRIM28 and PTGES2.,tissue specificity:Expressed at low levels in the lung, kidney and spleen.,

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