c-Fms (phospho Tyr723) rabbit pAb

c-Fms (phospho Tyr723) rabbit pAb

Item number: ES4843
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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c-Fms (phospho Tyr723) rabbit pAb

c-Fms (phospho Tyr723) rabbit pAb

$148.00

c-Fms (phospho Tyr723) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human M-CSF Receptor around the phosphorylation site of Tyr723. AA range:691-740
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
108kD
Geneid human
1436
Human swiss prot no
P07333
Cellular localization
Cell membrane; Single-pass type I membrane protein.
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],

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