Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cell membrane ; Lipid-anchor . Mitochondrion inner membrane . Nucleus . Cytoplasm, cytoskeleton . Cytoplasm, perinuclear region . Cell junction, focal adhesion . Localizes to focal adhesion sites following integrin engagement (PubMed:22801373). Localization to focal adhesion sites requires myristoylation and the SH3 domain (PubMed:7525268). Colocalizes with PDLIM4 at the perinuclear region, but not at focal adhesions (PubMed:19307596). .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
6714
Human swiss prot no
P12931
Immunogen
The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr216. AA range:181-230
Isotype
IgG
Observed band
50kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Product Citations
Product Citations
More Info
More Info
c-Src (phospho Tyr216) rabbit pAb
c-Src (phospho Tyr216) rabbit pAb
Vendor: ELK Biotechnology
SKU: ES7264
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cell membrane ; Lipid-anchor . Mitochondrion inner membrane . Nucleus . Cytoplasm, cytoskeleton . Cytoplasm, perinuclear region . Cell junction, focal adhesion . Localizes to focal adhesion sites following integrin engagement (PubMed:22801373). Localization to focal adhesion sites requires myristoylation and the SH3 domain (PubMed:7525268). Colocalizes with PDLIM4 at the perinuclear region, but not at focal adhesions (PubMed:19307596). .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
6714
Human swiss prot no
P12931
Immunogen
The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr216. AA range:181-230
Isotype
IgG
Observed band
50kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Product Citations
Product Citations
More Info
More Info
c-Src (phospho Tyr216) rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
