Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
cytoplasm,
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
767
Human swiss prot no
P35219
Immunogen
Synthesized peptide derived from the Internal region of human CA VIII.
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provid
Product Citations
Product Citations
More Info
More Info
CA VIII rabbit pAb
CA VIII rabbit pAb
Vendor: ELK Biotechnology
SKU: ES7546
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
cytoplasm,
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
767
Human swiss prot no
P35219
Immunogen
Synthesized peptide derived from the Internal region of human CA VIII.
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provid
Product Citations
Product Citations
More Info
More Info
CA VIII rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
