CA VIII rabbit pAb

CA VIII rabbit pAb

Item number: ES7546
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CA VIII rabbit pAb

CA VIII rabbit pAb

$148.00

CA VIII rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from the Internal region of human CA VIII.
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
767
Human swiss prot no
P35219
Cellular localization
cytoplasm,
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provid

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