CAD (phospho-Ser1859) rabbit pAb

Item number: ES17892
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CAD (phospho-Ser1859) rabbit pAb

$148.00

CAD (phospho-Ser1859) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB
Source
Rabbit
Recommended dilutions
WB 1:1000-2000
Immunogen
Synthesized phosho peptide around human CAD (Ser1859)
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
250kD
Geneid human
790
Human swiss prot no
P27708
Cellular localization
Cytoplasm . Nucleus . Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth.
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],

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