Product Overview

Applications

IHC;IF;ELISA

Cellular localization

Cytoplasm . Nucleus . Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth.

Clonality

Polyclonal

Concentration

1 mg/ml

Cost per item

Geneid human

790

Human swiss prot no

P27708

Immunogen

The antiserum was produced against synthesized peptide derived from human CAD around the phosphorylation site of Thr456. AA range:422-471

Isotype

IgG

Product weight

0.005kg

Reactivity

Human;Mouse

Recommended dilutions

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Documents

Manual

Background

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],

Product Citations

More Info

CAD (phospho Thr456) rabbit pAb

Vendor: ELK Biotechnology

SKU: ES7563

$148.00

Shipping calculated at checkout.

Documents

Manual

Available in stock (100)

Size: 50μL

50μL 100μL

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Product Overview

Applications

IHC;IF;ELISA

Cellular localization

Cytoplasm . Nucleus . Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth.

Clonality

Polyclonal

Concentration

1 mg/ml

Cost per item

Geneid human

790

Human swiss prot no

P27708

Immunogen

The antiserum was produced against synthesized peptide derived from human CAD around the phosphorylation site of Thr456. AA range:422-471

Isotype

IgG

Product weight

0.005kg

Reactivity

Human;Mouse

Recommended dilutions

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Documents

Manual

Background

Product Citations

More Info