Caldesmon (phospho Ser759) rabbit pAb

Caldesmon (phospho Ser759) rabbit pAb

Item number: ES7604
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Caldesmon (phospho Ser759) rabbit pAb

Caldesmon (phospho Ser759) rabbit pAb

$148.00

Caldesmon (phospho Ser759) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser759. AA range:725-774
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
800
Human swiss prot no
Q05682
Cellular localization
Cytoplasm, cytoskeleton . Cytoplasm, myofibril . Cytoplasm, cytoskeleton, stress fiber . On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle). .
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

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