CaMKK2 (phospho-Ser511) rabbit pAb

Item number: ES17866
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CaMKK2 (phospho-Ser511) rabbit pAb

$148.00

CaMKK2 (phospho-Ser511) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB
Source
Rabbit
Recommended dilutions
WB 1:1000-2000
Immunogen
Synthesized phosho peptide around human CaMKK2 (Ser511)
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
65kD
Geneid human
10645
Human swiss prot no
Q96RR4
Cellular localization
Nucleus . Cytoplasm . Cell projection, neuron projection . Predominantly nuclear in unstimulated cells, relocalizes into cytoplasm and neurites after forskolin induction. .
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012],

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