CaMKK2 (phospho-Ser511) rabbit pAb

Vendor: ELK Biotechnology

SKU: ES17866

$148.00

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Documents

Manual

Available in stock (100)

Size: 50μL

50μL 100μL

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Product Overview

Applications

WB

Cellular localization

Nucleus . Cytoplasm . Cell projection, neuron projection . Predominantly nuclear in unstimulated cells, relocalizes into cytoplasm and neurites after forskolin induction. .

Clonality

Polyclonal

Concentration

1 mg/ml

Cost per item

74

Geneid human

10645

Human swiss prot no

Q96RR4

Immunogen

Synthesized phosho peptide around human CaMKK2 (Ser511)

Isotype

IgG

Observed band

65kD

Product weight

0.005kg

Reactivity

Human;Mouse;Rat

Recommended dilutions

WB 1:1000-2000

Source

Rabbit

Storage

-20°C/1 year

Documents

Manual

Background

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012],

CaMKK2 (phospho-Ser511) rabbit pAb