CAMLG rabbit pAb

CAMLG rabbit pAb

Item number: ES9465
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CAMLG rabbit pAb

CAMLG rabbit pAb

$148.00

CAMLG rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
32kD
Geneid human
819
Human swiss prot no
P49069
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008],

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