Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
819
Human swiss prot no
P49069
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
32kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008],
Product Citations
Product Citations
More Info
More Info
CAMLG rabbit pAb
CAMLG rabbit pAb
Vendor: ELK Biotechnology
SKU: ES9465
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
819
Human swiss prot no
P49069
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
32kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008],
Product Citations
Product Citations
More Info
More Info
CAMLG rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per

