CAN6 rabbit pAb

Item number: ES9485
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CAN6 rabbit pAb

$148.00

CAN6 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
70kD
Geneid human
827
Human swiss prot no
Q9Y6Q1
Cellular localization
Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton, spindle . During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle.
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. [provided by RefSeq, Nov 2009],

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