CAPS1 rabbit pAb

CAPS1 rabbit pAb

Item number: ES17862
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CAPS1 rabbit pAb

CAPS1 rabbit pAb

$148.00

CAPS1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human; Mouse;Rat
Applications
WB
Source
Rabbit
Recommended dilutions
WB 1:500-2000
Immunogen
Synthesized peptide derived from human CAPS1 AA range: 1275-1325
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
8618
Human swiss prot no
Q9ULU8
Cellular localization
Cell junction, synapse . Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane ; Peripheral membrane protein . Membrane-associated to vesicles. Strongly enriched in synaptic fractions. Preferentially binds to dense core vesicles but not to synaptic vesicles. Binds phosphoinosides, with a strong selectivity for PtdIns(4,5)P2 over PtdIns(3,4,5)P3. Probably localizes to different vesicles compared to CADPS2. .
This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008],

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